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  • Modes of Coordination and Performance in Polycentric Governance

    Disentangling Complexity

    Series series Transformations in Governance
    Governance becomes ever more interconnected and multilevel, and polycentric governance has been developed as a lens to analyze this complexity. At an aggregate level, it explores whether multiple autonomous actors are able to coordinate across interdependent sectors, scales, and decision-making arenas. It remains unclear, however, which factors shape polycentric governance in a particular social ... Read more

    $102.99 CAD

  • Governing Complexity

    Analyzing and Applying Polycentricity

    Series series Cambridge Studies in Economics, Choice, and Society
    There has been a rapid expansion of academic interest and publications on polycentricity. In the contemporary world, nearly all governance situations are polycentric, but people are not necessarily used to thinking this way. Governing Complexity provides an updated explanation of the concept of polycentric governance. The editors provide examples of it in contemporary settings involving complex ... Read more

    $133.99 CAD

  • Immunosenescence

    Edited by Andreas Thiel ...
    Series series Biomedical and Life Sciences (R0)
    As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses ... Read more

    $128.09 CAD

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    Toward Routine Donor and Patient Antigen Profiling by DNA Analysis

    Series series Springer Nature Proceedings excluding Computer Science
    This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine. ... Read more

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  • Introduction to Molecular Medicine

    How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and ... Read more

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  • Molecular Mechanisms of Bacterial Infection via the Gut

    Edited by Chihiro Sasakawa ...
    Series series Biomedical and Life Sciences (R0)
    Our gut is colonized by numerous bacteria throughout our life, and the gut epithelium is constantly exposed to foreign microbes and dietary antigens. Thus, the gut epithelium acts as a barrier against microbial invaders and is equipped with various innate defense systems. Resident commensal and foreign invading bacteria interact intimately with the gut epithelium and can impact host cellular and ... Read more

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  • Semaphorins

    A Diversity of Emerging Physiological and Pathological Activities

    Edited by Atsushi Kumanogoh ...
    Series series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... Read more

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  • Therapeutic Vaccination Strategies

    Edited by P. Walden, W. Sterry, H. Hennekes ...
    Series series Medicine (R0)
    The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major ... Read more

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  • Introduction to Gastrointestinal Diseases Vol. 2

    Edited by Jakub Fichna ...
    Series series Medicine (R0)
    Learn the basics and more of gastrointestinal diseases.Gastrointestinal diseases have become a major medical, social and economic burden worldwide. The larger the number of patients suffering from gastric ulcer and colorectal cancer, the greater the need to properly diagnose and cure.This book is a comprehensive guide through GI diseases, which can be used by practitioners and patients. It will ... Read more

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  • Organelle Contact Sites

    From Molecular Mechanism to Disease

    Edited by Thomas Simmen, Mitsuo Tagaya ...
    Series series Biomedical and Life Sciences (R0)
    This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases.MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via ... Read more

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  • Metastasis of Colorectal Cancer

    Series series Biomedical and Life Sciences (R0)
    Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths.This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors ... Read more

    $256.99 CAD