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“daniel s sem”

Showing 1 - 12 of 12 results for “daniel s sem”
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  • Spectral Techniques In Proteomics

    Edited by Daniel S. Sem ...
    Facilitating the innovation, development, and application of new spectroscopic methods in proteomics, Spectral Techniques in Proteomics provides a broad overview of the spectroscopic toolbox that can be used, either with proteome or sub-proteome mixtures or with individual/purified proteins studied in parallel. It gives a modest overview of ... Read more

    $130.53 CAD

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  • Aggregation of Therapeutic Proteins

    Edited by Wei Wang, Christopher J. Roberts ...
    This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has ... Read more

    $183.99 CAD

  • Drug-Like Properties

    Concepts, Structure Design and Methods from ADME to Toxicity Optimization

    by Li Di, Edward H Kerns ...
    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and ... Read more

    $176.79 CAD

  • Drug-like Properties: Concepts, Structure Design and Methods

    from ADME to Toxicity Optimization

    by Li Di, Edward H Kerns ...
    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug ... Read more

    $88.79 CAD

  • Introduction to Proteins

    Structure, Function, and Motion, Second Edition

    by Amit Kessel, Nir Ben-Tal ...
    Series series Chapman & Hall/CRC Computational Biology Series
    Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, ... Read more

    $182.75 CAD

  • Drug Design

    Structure- and Ligand-Based Approaches

    Edited by Kenneth M. Merz, Jr, PhD, Dagmar Ringe, PhD, Charles H. Reynolds, PhD ...
    Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and commercial realms. This book provides a complete snapshot of the field of computer-aided drug design and associated experimental approaches. Topics covered include X-ray crystallography, NMR, fragment-based drug design, free energy methods, docking and scoring, ... Read more

    $142.39 CAD

  • NMR Metabolomics in Cancer Research

    by Miroslava Čuperlović-Culf ...
    Series series Woodhead Publishing Series in Biomedicine
    The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to ... Read more

    $234.39 CAD

  • Biotransformation and Metabolite Elucidation of Xenobiotics

    Characterization and Identification

    Edited by Ala F. Nassar ...
    The goal of this book is to improve the readers' knowledge of metabolite elucidation in drug metabolism by exposing them to in depth coverage of the biotransformation of xenobiotics, strategies for identifying and characterizing metabolites, FDA guidelines, and case studies on how to improve the decision-making process in structural modification of drug candidates to reduce toxicity.The book ... Read more

    $159.99 CAD

  • Biocatalysis: Biochemical Fundamentals And Applications (Second Edition)

    by Peter Grunwald ...
    In this Completely Revised and Extended Edition with a significantly enhanced content, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway ... Read more

    $85.79 CAD

  • Protein and Peptide Mass Spectrometry in Drug Discovery

    Edited by Michael L. Gross, Guodong Chen, Birendra Pramanik ...
    The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discoveryAn instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing ... Read more

    $186.99 CAD

  • Analytical Characterization of Biotherapeutics

    Edited by Jennie R. Lill, Wendy Sandoval ...
    The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics researchAnalytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for ... Read more

    $231.99 CAD

  • Protein and Peptide Folding, Misfolding, and Non-Folding

    by Vladimir Uversky ...
    Series Book 13 - Wiley Series in Protein and Peptide Science
    Sheds new light on intrinsically disordered proteins and peptides, including their role in neurodegenerative diseasesWith the discovery of intrinsically disordered proteins and peptides (IDPs), researchers realized that proteins do not necessarily adopt a well defined secondary and tertiary structure in order to perform biological functions. In fact, IDPs play biologically relevant roles, acting ... Read more

    $197.99 CAD