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Showing 1 - 12 of 16 results for “helmut buschmann”
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  • Drug Development Approaches for Poorly Soluble Compounds

    by Helmut Buschmann, Jörg Holenz, Christa Müller ...
    Series Book 85 - Methods & Principles in Medicinal Chemistry
    Ten proven strategies to overcome solubility challenges in drug developmentPoor water solubility prevents drug candidates from reaching their therapeutic targets, causing promising compounds to fail during development. Drug Development Approaches for Poorly Soluble Compounds presents ten distinct strategies for overcoming this challenge, from altering drug structure and creating prodrugs to ... Read more

    $165.99 CAD

  • Drug Selectivity

    An Evolving Concept in Medicinal Chemistry

    by Helmut Buschmann, Raimund Mannhold, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    The book "Drug Selectivity - An Evolving Concept in Medicinal Chemistry" provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process.The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects ... Read more

    $223.99 CAD

  • Biomolecular Simulations in Structure-Based Drug Discovery

    by Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    A guide to applying the power of modern simulation tools to better drug designBiomolecular Simulations in Structure-based Drug Discovery offers an up-to-date and comprehensive review of modern simulation tools and their applications in real-life drug discovery, for better and quicker results in structure-based drug design. The authors describe common tools used in the biomolecular simulation of ... Read more

    $167.99 CAD

  • New Drug Development for Known and Emerging Viruses

    by Helga Rübsamen-Schaeff, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decadesWritten by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease ... Read more

    $235.99 CAD

  • RNA as a Drug Target

    The Next Frontier for Medicinal Chemistry

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugsExisting paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize ... Read more

    $194.99 CAD

  • Open Access Databases and Datasets for Drug Discovery

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Open Access Databases and Datasets for Drug DiscoveryTimely resource discussing the future of data-driven drug discovery and the growing number of open-source databasesWith an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free ... Read more

    $194.99 CAD

  • Targeted Drug Delivery

    by Raimund Mannhold, Helmut Buschmann, Yogeshwar Bachhav, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Targeted Drug DeliveryNovel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugsTargeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug ... Read more

    $194.99 CAD

  • Flow and Microreactor Technology in Medicinal Chemistry

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz, Esther Alza ...
    Series series Methods & Principles in Medicinal Chemistry
    Learn to master a powerful technology to enable a faster drug discovery workflowThe ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled ... Read more

    $170.99 CAD

  • Neglected Tropical Diseases

    Drug Discovery and Development

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people.Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect ... Read more

    $199.99 CAD

  • Transporters as Drug Targets

    by Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets.Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug ... Read more

    $184.99 CAD

  • Epigenetic Drug Discovery

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins.Presented in three parts - Introduction to Epigenetics, General Aspects and Methodologies, and Epigenetic Target Classes - it covers everything any drug researcher would need in order to know ... Read more

    $223.99 CAD

  • Innovative Dosage Forms

    Design and Development at Early Stage

    by Raimund Mannhold, Helmut Buschmann, Jörg Holenz ...
    Series series Methods & Principles in Medicinal Chemistry
    Teaches future and current drug developers the latest innovations in drug formulation design and optimizationThis highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral ... Read more

    $187.99 CAD