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« alan prem kumar »

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  • Innovative Therapeutic Approaches by CRISPR/Cas9 in Cancer Therapy

    par Kiavash Hushmandi, Alan Prem Kumar ...
    This book explores the groundbreaking potential of CRISPR/Cas9 gene-editing technology in revolutionizing cancer treatment. This collection of chapters delves into the application of CRISPR/Cas9 across a variety of cancers, including lung, breast, brain, gastric, pancreatic, colorectal, liver, prostate, bladder, cervical, ovarian, and bone cancers. Each chapter provides an in-depth analysis of how ... En savoir plus

    $147.99 CAD

  • Autophagy, Apoptosis and Ferroptosis in Oncology

    Cell Death and Cancer

    par Kiavash Hushmandi, Alan Prem Kumar ...
    This book aims to provide a comprehensive exploration of three critical processes involved in cell death and survival, each playing a unique role in cancer development, progression, and treatment. Autophagy, apoptosis, and ferroptosis are distinct yet interconnected pathways that regulate cellular homeostasis and response to stress. In the context of oncology, these processes are of paramount ... En savoir plus

    $261.69 CAD

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  • Metabolism of Drugs and Other Xenobiotics

    Modifié par Pavel Anzenbacher, Ulrich M. Zanger ...
    A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook providessystematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviewsthe main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover ... En savoir plus

    $285.99 CAD

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Modifié par M. A. Hayat ...
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series ... En savoir plus

    $176.99 CAD

  • Medicinal Chemistry of Anticancer Drugs

    par Carmen Avendaño, J. Carlos Menéndez ...
    Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research ... En savoir plus

    $176.79 CAD

  • Cancer Drug Design and Discovery

    Modifié par Stephen Neidle ...
    The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumors. Unique sections ... En savoir plus

    $97.99 CAD

  • Cancer Stem Cells and Signaling Pathways

    Modifié par Surajit Pathak, Antara Banerjee ...
    Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater ... En savoir plus

    $155.99 CAD

  • The Heterogeneity of Cancer Metabolism

    Modifié par Anne Le ...
    Collections Livre 1311 - Advances in Experimental Medicine and Biology
    This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field.Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and ... En savoir plus

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  • Sirtuin Biology in Cancer and Metabolic Disease

    Cellular Pathways for Clinical Discovery

    Modifié par Kenneth Maiese ...
    Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders ... En savoir plus

    $145.99 CAD

  • Molecular, Cellular, and Metabolic Fundamentals of Human Aging

    par Evandro Fei Fang, Linda Hildegard Bergersen, Brian C. Gilmour ...
    Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, ... En savoir plus

    $132.99 CAD

  • Cytochrome P450 2D6

    Structure, Function, Regulation and Polymorphism

    par Shufeng Zhou ...
    Cytochromes are proteinsthat catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, ... En savoir plus

    $97.55 CAD

  • Cancer Drug Design and Discovery

    Modifié par Stephen Neidle ...
    Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted agents and more. This book includes several ... En savoir plus

    $115.99 CAD