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  • The Forgotten Cure

    The Past and Future of Phage Therapy

    par Anna Kuchment ...
    Collections series Biomedical and Life Sciences (R0)
    Before the arrival of penicillin in the 1940s, phage therapy was one of the few weapons doctors had against bacterial infections. It saved the life of Hollywood legend Tom Mix before being abandoned by Western science. Now, researchers and physicians are rediscovering the treatment, which pits phage viruses against their natural bacterial hosts, as a potential weapon against antibiotic-resistant ... En savoir plus

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    Collections series Biomedical and Life Sciences (R0)
    Scientific research on dengue has a long and rich history. The literature has been touched by famous names in medicine- Benjamin Rush, Walter Reed, and Albert Sabin, to name a very few- and has been fertile ground for medical historians . The advances made in those early investigations are all the more remarkable for the limited tools available at the time. The demonstration of a viral etiology ... En savoir plus

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  • Manual of Biological Markers of Disease

    A comprehensive reference work:This looseleaf work is an authoritative compilation of methods for the detection of autoantibodies (Section A: Methods of Autoantibody Detection); the structure, function, and molecular and biochemical concepts of autoantigens (Section B: Autoantigens); and the clinical significance of measuring autoantibodies in patients with rheumatic, connective tissue and ... En savoir plus

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  • Oxford Textbook of Medical Mycology

    Collections series Oxford Textbooks in Infectious Disease and Microbiology
    The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems-based approach to management, fungal disease in specific patient groups, ... En savoir plus

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  • Leptospira and Leptospirosis

    Modifié par Ben Adler ...
    Collections series Biomedical and Life Sciences (R0)
    This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral ... En savoir plus

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  • Chikungunya Virus

    Advances in Biology, Pathogenesis, and Treatment

    Modifié par Chioma M. Okeoma ...
    Collections series Biomedical and Life Sciences (R0)
    This book describes the molecular biology, pathogenesis, epidemiology, and potential strategies for control of chikungunya virus (CHIKV) infection. It offers insight into the structure and functions of CHIKV proteins as they relate to host response, interaction with the arthropod vector, and vaccination. A detailed account of both the epidemiological outlook and the clinical syndrome of CHIKV ... En savoir plus

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  • Genetic Immunization

    Wolf's discovery demonstrating that a reporter gene is expressed in myocytes subsequent to injection of naked DNA, was exploited by immunologists and vaccinologists to develop a new generation of vaccines. This observation galvanized the research and in a short lapse of time, an oceanic volume of knowledge has been accumulated. The research carried out in a variety of animal models showed the ... En savoir plus

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  • Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells

    Novel Insights into Disease Mechanisms

    Collections series Biomedical and Life Sciences (R0)
    Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and molecular response mechanisms to unveil novel insight into human health and disease. Since the ... En savoir plus

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  • Between Pathogenicity and Commensalism

    Collections series Biomedical and Life Sciences (R0)
    This comprehensive, interdisciplinary book covers different aspects of relevant human pathogens and commensals. The ongoing development of (meta-)genomic, transcriptomic, proteomic and bioinformatic analyses of pathogenic and commensal microorganisms and their host interaction provides a comprehensive introduction to the microbiological analysis of host-microbe interplay and its consequences for ... En savoir plus

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  • Influenza Pathogenesis and Control - Volume I

    Collections series Biomedical and Life Sciences (R0)
    This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, ... En savoir plus

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  • Marek’s Disease

    Modifié par K. Hirai ...
    Collections series Biomedical and Life Sciences (R0)
    Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. This serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well ... En savoir plus

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  • Muscle Gene Therapy

    Modifié par Dongsheng Duan ...
    Collections series Biomedical and Life Sciences (R0)
    Muscle disease represents an important health threat to the general population. There is essentially no cure. Gene therapy holds great promise to correct the genetic defects and eventually achieve full recovery in these diseases. Significant progresses have been made in the field of muscle gene therapy over the last few years. The development of novel gene delivery vectors has substantially ... En savoir plus

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