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A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment

Modifié par Natàlia Garcia-Reyero, Cheryl A. Murphy ...

Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of ... En savoir plus

$153.99 CAD

Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of
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Bad Pharma

How Drug Companies Mislead Doctors and Harm Patients

par Ben Goldacre ...

We all feel uncomfortable about the role of profit in healthcare, we all have a vague notion that the global $600bn pharmaceutical industry is somehow evil and untrustworthy, but that sense rarely goes beyond a flaky, undifferentiated new age worldview. Bad Pharma puts real flesh on those bones, revealing the rigged evidence used by drug companies. Bad information means bad treatment decisions, ... En savoir plus

$13.99 CAD

Aussi disponible en : Livre audio

We all feel uncomfortable about the role of profit in healthcare, we all have a vague notion that the global $600bn pharmaceutical industry is somehow evil and untrustworthy, but that sense rarely goes beyond a flaky, undifferentiated new age worldview. Bad Pharma puts real flesh on those bones, revealing the rigged evidence used by drug companies. Bad information means bad treatment decisions,
... En savoir plus

Aussi disponible en : Livre audio
Imaging Mass Spectrometry

Protocols for Mass Microscopy

Modifié par Mitsutoshi Setou ...

Collections series Biomedical and Life Sciences (R0)
Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening ... En savoir plus

$115.99 CAD

Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening
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Adrenaline

par Brian B. Hoffman ...

Famous as the catalyst of the fight or flight response, adrenaline has also received forensic attention as a perfect, untraceable poison—and rumors persist of its power to revive the dead. True to the spirit of its topic, Adrenaline is a stimulating journey that reveals the truth behind adrenaline’s scientific importance and popular appeal. ... En savoir plus

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Famous as the catalyst of the fight or flight response, adrenaline has also received forensic attention as a perfect, untraceable poison—and rumors persist of its power to revive the dead. True to the spirit of its topic, Adrenaline is a stimulating journey that reveals the truth behind adrenaline’s scientific importance and popular appeal.
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Histopathology of Preclinical Toxicity Studies

Interpretation and Relevance in Drug Safety Evaluation

par Peter Greaves ...

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature ... En savoir plus

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This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature
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The Biological Action of Physical Medicine

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The Biological Action of Physical Medicine: Controlling the Human Body's Information System challenges the contemporary way of thinking of diagnostics and therapy "from the outside." Drawing on 30 years of independent comprehensive research, this reference provides a universal and scientifically acceptable physiological theory, explaining the mode of action of methods of physical medicine as well ... En savoir plus

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Case Files Pharmacology, Third Edition

par Shelley A. Tischkau, Anush S. Pillai, Eugene C. Toy, David S. Loose ...

Collections series LANGE Case Files
REAL-LIFE CLINICAL CASES FOR THE BASIC SCIENCES AND USMLE STEP 1Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care. Case Files: Pharmacology provides 56 true-to-life clinical cases that illustrate essential concepts in pharmacology. Each case includes an easy-to-understand discussion correlated ... En savoir plus

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Informed and Healthy: Theoretical and Applied Perspectives on the Value of Information to Health Care focuses on two major issues: the value attributed to information by users and its effect on health care; and, a new model of information behavior in which the value of information drives various information activities (unlike many information models which tend to give prominence to information
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Technical Aspects of Toxicological Immunohistochemistry

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Collections series Biomedical and Life Sciences (R0)
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It ... En savoir plus

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Phosphatidylcholine

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This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven ... En savoir plus

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This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven
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A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment

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Bad Pharma

Imaging Mass Spectrometry

Adrenaline

Histopathology of Preclinical Toxicity Studies

The Biological Action of Physical Medicine

Case Files Pharmacology, Third Edition

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Informed and Healthy

Technical Aspects of Toxicological Immunohistochemistry

Phosphatidylcholine

Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

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