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  • Microbial Biochemistry

    par G.N. Cohen ...
    Collections series Biomedical and Life Sciences (R0)
    Microbial physiology, biochemistry, and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different permeability ... En savoir plus

    $204.99 CAD

  • Microbial Biochemistry

    par G. N. Cohen ...
    Collections series Biomedical and Life Sciences (R0)
    Microbial physiology, biochemistry and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different permeability ... En savoir plus

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  • Cystogenesis

    Modifié par Jong Hoon Park, Curie Ahn ...
    Collections series Biomedical and Life Sciences (R0)
    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating ... En savoir plus

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  • Of Fish, Fly, Worm, and Man

    Lessons from Developmental Biology for Human Gene Function and Disease

    Collections series Medicine (R0)
    The first complete genome sequence of a multicellular organism, Caenorhabditis elegans, has been determined recently. Several more will follow soon, among them the genome sequences of Drosophila melanogaster and the human. With these achievements, the stage is set for the next phase of "large-scale" biology, the study of the function of genes and the interactions between their protein products. ... En savoir plus

    $64.99 CAD

  • Viral Genome Replication

    Collections series Biomedical and Life Sciences (R0)

    $256.19 CAD

  • Mitochondria and Cancer

    Modifié par Keshav Singh, Leslie Costello ...
    Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration ... En savoir plus

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  • Patho-Epigenetics of Infectious Disease

    Collections series Biomedical and Life Sciences (R0)
    Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the ... En savoir plus

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  • Molecularly Targeted Therapy for Childhood Cancer

    Collections series Biomedical and Life Sciences (R0)
    Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered.This volume will provide a comprehensive summary of molecular ... En savoir plus

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  • The Hippo Signaling Pathway and Cancer

    Modifié par Moshe Oren, Yael Aylon ...
    Collections series Biomedical and Life Sciences (R0)
    The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many leading scientists are showing increased interest in this growing field and it's relation to cancer. The chapters in this volume cover virtually all aspects of tumor biology, because members of the Hippo Pathway have been associated with numerous well-established cell ... En savoir plus

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  • Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

    Modifié par John D. McKinney, Jean Pieters ...
    Collections series Biomedical and Life Sciences (R0)
    Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different ... En savoir plus

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  • Intrinsic Immunity

    Modifié par Bryan R. Cullen ...
    Collections series Biomedical and Life Sciences (R0)
    Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as ... En savoir plus

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  • Listen to the Music

    The Life of Hilary Koprowski

    par Roger Vaughan ...
    Collections series Biomedical and Life Sciences (R0)
    Dr. Hilary Koprowski is the pioneer of live polio vaccine, the first researcher to advance the diagnostic and therapeutic use of monoclonal antibodies, and the developer of the "gold standard" rabies vaccine. This biography chronicles his distinguished career and life's work in the field of microbiology. A world-reknowned maverick in biomedical research, Koprowski's research methods were often ... En savoir plus

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