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  • The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy

    Collections series Biomedical and Life Sciences (R0)
    This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. ... En savoir plus

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  • The Human Hippocampus

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    Collections series Medicine (R0)
    This new edition, like previous ones, offers a precise description of the anatomy of the human hippocampus based upon neurosurgical progress and the wealth of medical imaging methods available. The first part describes the fine structures of the hippocampus and is illustrated with new original figures. A survey is then provided of current concepts explaining the functions of the hippocampus, and ... En savoir plus

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  • Cardiovascular and Musculoskeletal Systems

    Collections series Medicine (R0)
    This is the ninth volume in a series dealing with induced lesions in laboratory animals. The information on pathology and toxicology documented in the series is an aid to scientific institutions, industry and government agencies charged with the safety testing of food, drugs and chemicals. ... En savoir plus

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  • Advances in Down Syndrome Research

    Modifié par Gert Lubec ...
    Collections series Medicine (R0)
    "Advances in Down Syndrome Research” represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell ... En savoir plus

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  • Stem Cells and Cancer Stem Cells, Volume 5

    Therapeutic Applications in Disease and Injury

    Modifié par M.A. Hayat ...
    Collections series Biomedical and Life Sciences (R0)
    It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the ... En savoir plus

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  • Wilson’s Disease

    A Clinician’s Guide to Recognition, Diagnosis, and Management

    Movement disorder specialists, general neurologists, hepatologists, general gastroenterologists, and psychiatrists are the specialists who will most likely see some Wilson's disease patients during their careers. See them - yes. Recognize and diagnose them - maybe. If you are in one of these specialties, and a patient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, or mood disorder, is ... En savoir plus

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  • Texture of the Nervous System of Man and the Vertebrates

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    Traduit par P. Pasik, T. Pasik ...
    Most scientists agree that the 21st century will be the "Century of Biology". The revolution that started a few decades ago with the extraordinary develop ment of molecular biology, has provided the basis for the understanding of the mechanisms that govern life through the regulation of cell function and cell-to cell interactions. Neuroscience will surely be one of the biological disciplines that ... En savoir plus

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  • Maternal Influences on Fetal Neurodevelopment

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    Collections series Medicine (R0)
    Novel Approaches into the Origins of Neurodevelopmental Disorders: The Fetal Physiology Foundation Over the past two decades, autism, a neurodevelopmental disorder that is defined by behavior and was once believed to be rare, became recognized in increasing numbers of children and recently received distinction as an “epidemic” [1]. While numbers of affected children have steadily increased, our ... En savoir plus

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  • Retinal Degenerative Diseases

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    Collections series Springer Nature Proceedings excluding Computer Science
    This book will contain the proceedings of the XV International Symposium on Retinal Degeneration (RD2012). A majority of those who will speak and present posters at the meeting will contribute to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with ... En savoir plus

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  • Biopsy Diagnosis of Peripheral Neuropathy

    Collections series Medicine (R0)
    Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic ... En savoir plus

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  • Neuropathology

    Collections series Medicine (R0)
    Increasing specialisation in pathology reflects the progressive changes in medical practise. The advent of a specialist with a new interest in a hospital or clinic may present the pathologist with a need to extend his or her knowledge to be able to work closely with the clinical practi tioner in order to provide adequate clinical care. Some sub-specialisations are long established, such a one is ... En savoir plus

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  • Animal Models of Behavior Genetics

    Modifié par Jonathan C. Gewirtz, Yong-Kyu Kim ...
    Collections series Advances in Behavior Genetics
    This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The ... En savoir plus

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