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  • Toxikologie für Einsteiger

    Collections series Life Science and Basic Disciplines (German Language)
    In diesem kurzen Lehrbuch werden grundlegende wissenschaftliche und klinische Aspekte der Toxikologie dargestellt und ihre wichtigsten Inhalte, Ziele und Aufgaben beschrieben. Das Buch richtet sich an Studierende biowissenschaftlicher und chemischer Bachelor- und Masterstudiengänge, die Toxikologie als medizinisches Wahlfach belegen. Zu Beginn werden wichtige toxikologische Fachbegriffe definiert, ... En savoir plus

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  • Uptake and Trafficking of Protein Toxins

    Modifié par Holger Barth ...
    Collections series Biomedical and Life Sciences (R0)
    This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary ... En savoir plus

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    **"A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times“Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—NatureThe epic and controversial story of a major breakthrough ... En savoir plus

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  • Antimicrobial Therapy Guide®, 19th edition

    The leading clinical reference source on therapeutic antimicrobials, this latest edition contains up-to-date treatment guidelines and algorithms for most infections in an expanded, easy-to-read format. Composed by a team of expert contributing editors, this book is conveniently organized and tabbed for quick reference of drug toxicities, prophylaxis strategies, and dosage options. Now available ... En savoir plus

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  • Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

    Collections series Medicine (R0)
    Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be ... En savoir plus

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  • Crossroads Between Innate and Adaptive Immunity IV

    Collections series Biomedical and Life Sciences (R0)
    This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen ... En savoir plus

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  • Chemokine Receptors and NeuroAIDS

    Beyond Co-Receptor Function and Links to Other Neuropathologies

    Modifié par Olimpia Meucci ...
    Collections series Biomedical and Life Sciences (R0)
    Chemokine Receptors and NeuroAIDS: Beyond the Co-receptor Function and Links to Other Neuropathologies focuses on unresolved or emerging issues concerning the role of chemokine receptors in neuronal injury and HIV neuropathology, including their ability to regulate fundamental neuronal and glial functions and their role in neurovirulence and neurotoxicity. Although the importance of these ... En savoir plus

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  • Human Health

    The Contribution of Microorganisms

    Modifié par Stewart A.W. Gibson ...
    Collections series Biomedical and Life Sciences (R0)
    Human Health: The Contribution of Microorganisms is the first major work to concentrate on probiotics in humans. It presents both new and established data on the origins and importance of commensal floras, the history and characteristics of probiotics, the use of probiotics in clinical situations, and preclinical and volunteer studies. It also covers commercial issues such as the difficulties ... En savoir plus

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  • Novel Strategies in the Design and Production of Vaccines

    Modifié par Sara Cohen, Avigdor Shafferman ...
    Collections series Biomedical and Life Sciences (R0)
    Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from ... En savoir plus

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  • Modern Vaccinology

    Modifié par Edouard Kurstak ...
    The recent developments in modern vaccinology are mainly based on: (i) cloning of microbial genes into recombinant vectors containing genetic information for expression of desired neutralizing immunogens; (ii) alternatives of attenuated vectors with deleted genes permitting the insertion of several foreign genes expressing antigens exposed to the host immune system during the abortive replication ... En savoir plus

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  • Current Topics in Innate Immunity II

    Collections series Biomedical and Life Sciences (R0)
    Mounting evidence in the past decade indicates that innate immunity mediates functions above and beyond first-line defense against infection. It is now appreciated that innate immune mechanisms are critically involved in the development of adaptive immunity and, moreover, the regulation of diverse physiological and homeostatic processes. The latter explains why deregulation of innate immunity may ... En savoir plus

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