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  • Adverse Drug Reactions

    Modifié par Jack Uetrecht ...
    Collections series Biomedical and Life Sciences (R0)
    This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug ... En savoir plus

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  • Hepatitis C Virus: From Molecular Virology to Antiviral Therapy

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    Collections series Biomedical and Life Sciences (R0)
    Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of ... En savoir plus

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  • Therapeutic Vaccination Strategies

    Modifié par P. Walden, W. Sterry, H. Hennekes ...
    Collections series Medicine (R0)
    The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major ... En savoir plus

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  • Laparoscopic Liver Resection

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    Collections series Medicine (R0)
    This book provides a comprehensive guide to the use of laparoscopic resection in the treatment of surgical liver lesions. As it introduces the steps and key techniques of laparoscopic anatomical liver resection, it will be of great interest to surgeons and physicians working in this area. Though each chapter covers a different technique, all chapters are written in a uniform style, including ... En savoir plus

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  • Sucralfate

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    Collections series Medicine (R0)
    International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future ... En savoir plus

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  • Immunological Aspects of Liver Disease

    Collections series Medicine (R0)
    Howard C. Thomas In normal subjects the regulatory apparatus of the immune system permits responses to foreign antigens but suppresses those directed to "self' components. Autoimmune disease occurs as a failure ofthis system either as a result of a primary defect in the regulatory apparatus (primary autoimmunization) or because of a change in the antigenicity of the tissues (secondary ... En savoir plus

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  • Interstitial, Endocavitary and Perfusional Hyperthermia

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    Collections series Thermotherapy
    "Internal" hyperthermia is a type of thermotherapy by which heat is sup plied to tumor tissue in situ. There are three different techniques for pro viding internal hyperthermia: (1) interstitial hyperthermia using implanted needle probes, (2) intracavitary hyperthermia using probes introduced into natural body cavities, and (3) perfusional hyperthermia by means of ex tracorporal blood heating. ... En savoir plus

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  • Sandostatin® in the Treatment of Gastroenteropancreatic Endocrine Tumors

    Consensus Round Table, Scottsdale (Arizona), March 22, 1987

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    The secretion of bioactive products by tumors of the gastroenteropancreatic system results in the development of watery diarrhea that can lead to death in a very short period if not brought under control. Even if the consequences are less dramatic, the patients' ability to lead a normal daily life is seriously impaired, and they may become severely depressed. SandostatinR alleviates the condition ... En savoir plus

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  • Drug Transporters

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  • Viral Hepatitis and Liver Disease

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    A series of international symposia on viral hepatitis and liver disease has been held triannially, and called the "Olympics" of this research field. Our book presents the results of the eighth of these "Olympiads" which for the first time, was held in Asia (May 1993, Tokyo). Due to the rapid progress in research on both basic and clinical aspects of viral hepatitis and liver disease, the state of ... En savoir plus

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  • Pancreatic Fistulas

    Introducing this monograph by expressing our heartfeIt thanks to all those who have contributed to its success may seem no more than a rhetorical exercise. However, at the same time we feel duty bound to add our sincere apologies, for we know that many of the dis tinguished authors of the various chapters have been hard put to find any relevant information in the existing literature. The plain ... En savoir plus

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