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The James Naismith Reader

Basketball in His Own Words

par James Naismith ...

James Naismith invented the game of basketball as a physical education instructor at the International YMCA Training School in Springfield, Massachusetts. That December of 1891, his task was to create a game to occupy a rowdy class during the winter months. Almost instantly popular, the game spread across the country and was played in fifteen countries by the end of the century. And yet basketball ... En savoir plus

$25.99 CAD

James Naismith invented the game of basketball as a physical education instructor at the International YMCA Training School in Springfield, Massachusetts. That December of 1891, his task was to create a game to occupy a rowdy class during the winter months. Almost instantly popular, the game spread across the country and was played in fifteen countries by the end of the century. And yet basketball
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Cyclic Peptides

From Bioorganic Synthesis to Applications

Modifié par Jesko Koehnke, James Naismith, Wilfred A van der Donk ...

Collections Livre 6 - Chemical Biology
Cyclic peptides are increasingly employed as chemical tools in biology and drug discovery. They have gained a lot of interest as alternative sources of new drugs to traditional small molecules.This book introduces cyclic peptides and provides a thorough overview of biosynthetic and fully synthetic approaches to their preparation. Following an introduction to cyclic peptides, biosynthetic and ... En savoir plus

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Cyclic peptides are increasingly employed as chemical tools in biology and drug discovery. They have gained a lot of interest as alternative sources of new drugs to traditional small molecules.This book introduces cyclic peptides and provides a thorough overview of biosynthetic and fully synthetic approaches to their preparation. Following an introduction to cyclic peptides, biosynthetic and
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Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

par Andrew B. Hughes ...

Collections Livre 4 - Amino Acids, Peptides and Proteins in Organic Chemistry
This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series.Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a ... En savoir plus

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This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series.Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a
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The Organic Chemistry of Drug Design and Drug Action

par Richard B. Silverman ...

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes ... En savoir plus

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Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes
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Metabolomics in Practice

Successful Strategies to Generate and Analyze Metabolic Data

Modifié par Wolfram Weckwerth, Michael Lämmerhofer ...

Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the ... En savoir plus

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Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the
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Peptides

Synthesis, Structures, and Applications

Modifié par Bernd Gutte ...

In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors ... En savoir plus

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In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors
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Chemical Genomics

Modifié par Haian Fu, PhD ...

Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of ... En savoir plus

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Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of
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The Chemical Biology of Nucleic Acids

par Günter Mayer ...

With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include:chemical synthesis of modified RNAexpansion of the genetic alphabet in nucleic acids by ... En savoir plus

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With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include:chemical synthesis of modified RNAexpansion of the genetic alphabet in nucleic acids by
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Biomimetic Organic Synthesis

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In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature.Volume 1 describes the biomimetic synthesis of alkaloids.Volume 2 covers terpenes, polyketides, and polyphenols.A discussion of the current challenges and frontiers in ... En savoir plus

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In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature.Volume 1 describes the biomimetic synthesis of alkaloids.Volume 2 covers terpenes, polyketides, and polyphenols.A discussion of the current challenges and frontiers in
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Protein Surface Recognition

Approaches for Drug Discovery

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A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key ... En savoir plus

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A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key
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Structural Aspects Of Protein Synthesis (2nd Edition)

par Anders Liljas, Mans Ehrenberg ...

Collections Livre 1 - Series In Structural Biology
This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and ... En savoir plus

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This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and
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Peptidomimetics in Organic and Medicinal Chemistry

The Art of Transforming Peptides in Drugs

par Antonio Guarna, Andrea Trabocchi ...

A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands.Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the ... En savoir plus

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A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands.Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the
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Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

The Organic Chemistry of Drug Design and Drug Action

Metabolomics in Practice

Peptides

Chemical Genomics

The Chemical Biology of Nucleic Acids

Biomimetic Organic Synthesis

Protein Surface Recognition

Structural Aspects Of Protein Synthesis (2nd Edition)

Peptidomimetics in Organic and Medicinal Chemistry

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