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  • Mitochondria and Neurotoxicity

    Collections Livre 13 - Advances in Neurotoxicology
    Mitochondria and Neurotoxicity, Volume Thirteen in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Introduction to mitochondrial toxicity: form, function, and signaling, Respirometry parameters as indicators of neurotoxicity, Pesticide exposure and hippocampal neurogenesis: Role of ER stress ... En savoir plus

    $190.39 CAD

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  • Protein Misfolding Diseases

    Current and Emerging Principles and Therapies

    Collections Livre 14 - Wiley Series in Protein and Peptide Science
    An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific ... En savoir plus

    $282.99 CAD

  • Stem Cells

    From Biology to Therapy, 2 Volumes

    Modifié par Robert A. Meyers ...
    Collections series Advances in Molecular Biology and Medicine
    This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with ... En savoir plus

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  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Modifié par Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... En savoir plus

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  • Handbook of Epigenetics

    The New Molecular and Medical Genetics

    Modifié par Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related ... En savoir plus

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  • The AH Receptor in Biology and Toxicology

    This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this ... En savoir plus

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  • Epigenetics in Human Disease

    Modifié par Trygve O. Tollefsbol ...
    Collections series Translational Epigenetics
    Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the ... En savoir plus

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  • Epigenetics in Human Disease

    Modifié par Trygve O. Tollefsbol ...
    Collections series Translational Epigenetics
    Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel ... En savoir plus

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  • Estrogen — Mystery Drug for the Brain?

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  • Molecular, Cellular, and Metabolic Fundamentals of Human Aging

    Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, ... En savoir plus

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  • Sarcopenia – Age-Related Muscle Wasting and Weakness

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    Modifié par Gordon S. Lynch ...
    Collections series Biomedical and Life Sciences (R0)
    Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the ... En savoir plus

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  • Mitochondrial DNA, Mitochondria, Disease and Stem Cells

    Modifié par Justin C. St. John ...
    Collections series Biomedical and Life Sciences (R0)
    This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and ... En savoir plus

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