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« robert rothlein »

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  • Structure, Function, and Regulation of Molecules Involved in Leukocyte Adhesion

    Modifié par Peter E. Lipsky, Robert Rothlein, Takashi K. Kishimoto, Ronald B. Faanes, C.Wayne Smith ...
    Leukocyte adhesion molecules have been the subject of intense basic and preclinical research. Results from clinical trials obtained sofar with antibodies directed towards these surface proteins offer promise for the prevention of graft rejection and effective treatment of acute and chronic inflammatory disease. This volume presents a comprehensive review of contemporary research on the structure, ... En savoir plus

    $64.09 CAD

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  • New Insights to Neuroimmune Biology

    Modifié par Istvan Berczi ...
    New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, neurogenic inflammation, the ... En savoir plus

    $150.99 CAD

  • MIF Family Cytokines in Innate Immunity and Homeostasis

    Modifié par Richard Bucala, Jürgen Bernhagen ...
    Collections series Medicine (R0)
    The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress ... En savoir plus

    $179.39 CAD

  • Anti-Idiotypes, Receptors, and Molecular Mimicry

    Modifié par D. Scott Linthicum, Nadir R. Farid ...
    Collections series Medicine (R0)
    Here is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin ... En savoir plus

    $64.99 CAD

  • The Inflammasomes

    Modifié par Isabelle Couillin, Virginie Pétrilli, Fabio Martinon ...
    Collections series Medicine (R0)
    The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the ... En savoir plus

    $179.39 CAD

  • Autophagy Networks in Inflammation

    Modifié par Maria Chiara Maiuri, Daniela De Stefano ...
    Collections series Medicine (R0)
    Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been ... En savoir plus

    $179.39 CAD

  • IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity

    Modifié par Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova ...
    Collections series Medicine (R0)
    The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition “Th17 Cells: Role in Inflammation and Autoimmune Disease” in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate ... En savoir plus

    $256.19 CAD

  • TH17 Cells in Health and Disease

    Modifié par Shuiping Jiang ...
    Collections series Biomedical and Life Sciences (R0)
    “About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation. However, TH1 / TH2 paradigm could not adequately explain development of certain inflammatory responses which provided ... En savoir plus

    $256.99 CAD

  • Proteases and Their Receptors in Inflammation

    Modifié par Nathalie Vergnolle, Michel Chignard ...
    Collections series Medicine (R0)
    Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or ... En savoir plus

    $179.39 CAD

  • Advances in Immunology

    Modifié par Frederick W. Alt ...
    Collections Livre 86 - Advances in Immunology
    Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, ... En savoir plus

    $172.99 CAD

  • Human Fungal Pathogens

    Modifié par Oliver Kurzai ...
    Collections series Biomedical and Life Sciences (R0)
    Whereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world ... En savoir plus

    $344.59 CAD

  • Hematopoietic Stem Cell Biology

    Modifié par Motonari Kondo ...
    Collections series Biomedical and Life Sciences (R0)
    In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in ... En savoir plus

    $128.99 CAD