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Biology of Antibiotics

par Hans Zähner, Werner K. Maas ...

Collections series Medicine (R0)
This book is based on Hans Zahner's Biologie der Antibiotica, published in 1965. There is a vast literature on antibiotics, covering chemical, phar macological, and clinical aspects. We have made no attempt to cover this literature comprehensively. Our effort is directed toward discuss ing antibiotics as biological agents. They are substances produced by living cells, yet they are able to inhibit ... En savoir plus

$64.99 CAD

This book is based on Hans Zahner's Biologie der Antibiotica, published in 1965. There is a vast literature on antibiotics, covering chemical, phar macological, and clinical aspects. We have made no attempt to cover this literature comprehensively. Our effort is directed toward discuss ing antibiotics as biological agents. They are substances produced by living cells, yet they are able to inhibit
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Principles and Practice of Clinical Research

Modifié par Frederick P Ognibene, John I. Gallin ...

The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory ... En savoir plus

$110.39 CAD

The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory
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Validation of Alternative Methods for Toxicity Testing

Modifié par Chantra Eskes, Maurice Whelan ...

Collections series Biomedical and Life Sciences (R0)
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and ... En savoir plus

$204.99 CAD

This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and
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Biopharmaceutical Drug Design and Development

Modifié par Susanna Wu-Pong ...

Collections series Biomedical and Life Sciences (R0)
New discoveries in biology are occurring at an incredible rate, and with these discoveries arise nearly unimaginable opportunities in every area of human existence. Imagine the excitement surround ing the "penicillin project" and the subsequent rapid development of anti-infective agents that took place in the 1940s and 1950s. Fast for ward to the world today and our ability to treat life ... En savoir plus

$102.99 CAD

New discoveries in biology are occurring at an incredible rate, and with these discoveries arise nearly unimaginable opportunities in every area of human existence. Imagine the excitement surround ing the "penicillin project" and the subsequent rapid development of anti-infective agents that took place in the 1940s and 1950s. Fast for ward to the world today and our ability to treat life
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Supramolecular Chemistry

From Biological Inspiration to Biomedical Applications

par Peter J. Cragg ...

Collections series Chemistry and Material Science (R0)
The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field.Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application ... En savoir plus

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The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field.Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application
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Anticancer Genes

Modifié par Stefan Grimm ...

Collections series Biomedical and Life Sciences (R0)
This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis, ... En savoir plus

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This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis,
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Heparin - A Century of Progress

Modifié par Clive P. Page, Rebecca Lever, Barbara Mulloy ...

Collections series Biomedical and Life Sciences (R0)
Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the ... En savoir plus

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Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the
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Pharmacotherapy of Pulmonary Hypertension

Modifié par Marc Humbert, Oleg V. Evgenov, Johannes-Peter Stasch ...

Collections series Biomedical and Life Sciences (R0)
This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle ... En savoir plus

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This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle
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Sex and Gender Differences in Pharmacology

Modifié par Vera Regitz-Zagrosek ...

Collections series Biomedical and Life Sciences (R0)
This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion ... En savoir plus

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This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion
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Cell Culture in Pharmaceutical Research

Modifié par N.E. Fusenig, H. Graf ...

Collections series Medicine (R0)
Cell biology has made an appreciable impact on the evaluation of physiological and pathophysiological processes leading to a more detailed understanding of the signaling mechanisms by which cells communicate in vivo and in vitro and modify adaptively. By using cell culture models in addition to animal experiments we are now able to better define the overall and the selective potential of drugs. ... En savoir plus

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Cell biology has made an appreciable impact on the evaluation of physiological and pathophysiological processes leading to a more detailed understanding of the signaling mechanisms by which cells communicate in vivo and in vitro and modify adaptively. By using cell culture models in addition to animal experiments we are now able to better define the overall and the selective potential of drugs.
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Adverse Effects of Herbal Drugs

par G. Abel, R. Bos, I.H. Bowen, R.F. Chandler, D. Corrigan, I.J. Cubbin, P.A.G.M: De Smet, N. Pras, J-.J.C. Scheffer, T.A. Van Beek, W. Van Uden, H.J. Woerdenbag ...

Collections series Biomedical and Life Sciences (R0)
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Therapeutic Vaccination Strategies

Modifié par P. Walden, W. Sterry, H. Hennekes ...

Collections series Medicine (R0)
The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major ... En savoir plus

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The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major
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Principles and Practice of Clinical Research

Validation of Alternative Methods for Toxicity Testing

Biopharmaceutical Drug Design and Development

Supramolecular Chemistry

Anticancer Genes

Heparin - A Century of Progress

Pharmacotherapy of Pulmonary Hypertension

Sex and Gender Differences in Pharmacology

Cell Culture in Pharmaceutical Research

Adverse Effects of Herbal Drugs

Therapeutic Vaccination Strategies

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