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  • Therapeutic Targeting of RAS Mutant Cancers

    Series series Elements in Molecular Oncology
    The KRAS oncogene is believed to be the most common single nucleotide variant oncogene in human cancer. Historically, efforts to target KRAS and the other RAS GTPases have struggled. More recently, efforts have focused on identifying and exploiting features unique to specific oncogenic mutations. This has led to the first FDA approval for a RAS targeted therapy. This new agent is a covalent ... Read more

    $20.99 USD

  • Gender, Climate Change and Livelihoods

    Vulnerabilities and Adaptations

    This book applies a gendered lens to evaluate the dynamic linkages between climate change and livelihoods in developing countries. It examines how climate change affects women and men in distinct ways, and what the implications are for earning income and accessing the natural, social, economic, and political resources required to survive and thrive. The book's contributing authors analyze the ... Read more

    $109.99 USD

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  • Human Security and Sustainable Development in East Africa

    Series series Routledge Studies in Peace, Conflict and Security in Africa
    This book investigates contemporary human security issues in East Africa, setting forth policy recommendations and a research agenda for future studies.Human security takes a people-centered rather than state-centered approach to security issues, focusing on whether people feel safe, free from fear, want, and indignity. This book investigates human security in East Africa, encompassing issues as ... Read more

    Free

  • Science and Technology for Development

    by James Smith ...
    Series series Development Matters
    How can science realize its potential and help us tackle global inequality, environmental change and crippling poverty? How can more appropriate technologies be developed for those most in need? Science has long promised much -- new crops, new medicines, new sources of energy, new means of communication -- but the potential of new technologies has frequently bypassed the poorest people and the ... Read more

    $26.99 USD

  • Protein Kinase CK2

    Series Book 6 - The Wiley-IUBMB Series on Biochemistry and Molecular Biology
    Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its ... Read more

    $194.00 USD

  • Green Social Work

    From Environmental Crises to Environmental Justice

    Social work is the profession that claims to intervene to enhance people's well-being. However, social workers have played a low-key role in environmental issues that increasingly impact on people's well-being, both locally and globally.This compelling new contribution confronts this topic head-on, examining environmental issues from a social work perspective. Lena Dominelli draws attention to the ... Read more

    $24.00 USD

  • Cancer Stem Cells

    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... Read more

    $178.00 USD

  • Population and Society

    An Introduction

    This exciting new book presents the field of social demography, animating the study of population with a vibrant sociological imagination. Gregg Lee Carter provides multiple demonstrations of how taking a demographic perspective can give us a better understanding of social phenomena once thought to be largely the products of culture, politics, or the economy.Five key chapters concentrate on (1) ... Read more

    $25.00 USD

  • The Social Dimensions Of Climate Change: Equity And Vulnerability In A Warming World

    Climate change is arguably the most profound challenge facing the international community in the 21st century. It is as much a challenge for poverty reduction, growth and development as it is a global environmental issue. It could undermine or reverse progress in reducing poverty and attaining the Millenium Development Goals, thereby unraveling many of the development gains of recent decades. It ... Read more

    $14.99 USD

  • Untranslated Gene Regions and Other Non-coding Elements

    Regulation of Eukaryotic Gene Expression

    Series series Biomedical and Life Sciences (R0)
    There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous ... Read more

    $49.99 USD

  • Cities, Disaster Risk and Adaptation

    Series series Routledge Critical Introductions to Urbanism and the City
    Worldwide, disasters and climate change pose a serious risk to sustainable urban development, resulting in escalating human and economic costs. Consequently, city authorities and other urban actors face the challenge of integrating risk reduction and adaptation strategies into their work. However, related knowledge and expertise are still scarce and fragmented.Cities, Disaster Risk and Adaptation ... Read more

    $80.99 USD

  • PI3K-mTOR in Cancer and Cancer Therapy

    Series series Medicine (R0)
    In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR ... Read more

    $143.99 USD