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Top Series in United States

Showing 1 - 12 of 12 results for “kendra paskvan”
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  • Therapeutic Targeting of RAS Mutant Cancers

    by Edward C. Stites, Kendra Paskvan, Shumei Kato ...
    Series series Elements in Molecular Oncology
    The KRAS oncogene is believed to be the most common single nucleotide variant oncogene in human cancer. Historically, efforts to target KRAS and the other RAS GTPases have struggled. More recently, efforts have focused on identifying and exploiting features unique to specific oncogenic mutations. This has led to the first FDA approval for a RAS targeted therapy. This new agent is a covalent ... Read more

    $20.99 USD

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  • Protein Kinase CK2

    by Lorenzo A. Pinna ...
    Series Book 6 - The Wiley-IUBMB Series on Biochemistry and Molecular Biology
    Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its ... Read more

    $194.00 USD

  • Cancer Stem Cells

    by Vinagolu K. Rajasekhar ...
    Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, ... Read more

    $178.00 USD

  • Untranslated Gene Regions and Other Non-coding Elements

    Regulation of Eukaryotic Gene Expression

    by Sue Fletcher, Steve D. Wilton, Lucy W. Barrett ...
    Series series Biomedical and Life Sciences (R0)
    There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous ... Read more

    $49.99 USD

  • PI3K-mTOR in Cancer and Cancer Therapy

    Edited by Nandini Dey, Pradip De, Brian Leyland-Jones ...
    Series series Medicine (R0)
    In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR ... Read more

    $143.99 USD

  • Protein Quality Control in Neurodegenerative Diseases

    Edited by Richard I. Morimoto, Yves Christen ...
    Series series Biomedical and Life Sciences (R0)
    The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a ... Read more

    $143.09 USD

  • Long Non-coding RNAs in Human Disease

    Edited by Kevin V. Morris ...
    Series series Biomedical and Life Sciences (R0)
    This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the ... Read more

    $89.99 USD

  • Influence of FOX genes on aging and aging-associated diseases

    by Elena Tschumak ...
    FOX genes have different regulatory functions and influence aging, carcinogenesis, neurodegeneration etc. They can directly, indirectly, via interaction with homo-, heterodimers and other factors effect its target genes and thus influence RUNX, ROBO, CREB, RELN, FOXO1, POT1, telomerase , DYRK1A, PTEN, NCAM1, VLDLR, Vitamin D and others. MiRNA modulation, alternative splicing, sumoilation, ... Read more

    $1.99 USD or Free with Kobo Plus

  • Advances in Cancer Drug Targets (Volume 1)

    by Atta-ur-Rahman ...
    Series Book 1 - Advances in Cancer Drug Targets
    Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling ... Read more

    $20.89 USD

  • Targeting Autophagy in Cancer Therapy

    Edited by Jin-Ming Yang ...
    Series series Medicine (R0)
    This volume will detail the current state and perspectives of autophagy-based cancer therapy. Covering a wide range of topics, it will include an overview of autophagy as a therapeutic target in cancer, autophagy modulators as cancer therapeutic agents, implications of micro-RNA-regulated autophagy in cancer therapy, modulation of autophagy through targeting PI3 kinase in cancer therapy, targeting ... Read more

    $89.99 USD

  • Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development

    Edited by Constanze Bonifer, Peter N. Cockerill ...
    Series series Biomedical and Life Sciences (R0)
    During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at ... Read more

    $143.09 USD

  • Cell Cycle Deregulation in Cancer

    Edited by Greg H. Enders ...
    Series series Medicine (R0)
    Cancer is fundamentally a disease of abnormal cell proliferation: Cancer cells multiply when and where they should not. This proliferation entails escape from normal bounds imposed by the tissue environment, the internal biology of the cell (DNA damage, chromosomal imbalances, disorganized mitotic spindles), and the proliferative history of the cell (normal generational times). Some of the key ... Read more

    $143.09 USD