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1 - 12 de 12 resultados para “john m lambert”
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  • Early Paleoindians in the Upper Midcontinent of North America

    Lithic Procurement, Settlement Mobility, and Social Interaction

    de Christopher J. Ellis, Melissa I. Pardi, Christopher C. Widga, Ryan M. Parish, Scott Eckford, D. Bryan Deller, William Fox, Adrian Burke, Peter L. Storck, Peter J. Barnett, L. Denis Delorme, Stephen Monckton, John Tomenchuk, Peter H. von Bitter, Bern Feenstra, Frank Crist Jr., Dan Long, Alan Morgan, Jonathan C. Lothrop, Susan Winchell-Sweeney, Kevin Smith, Mark F. Seeman, Edward W. Herrmann, Mackenzie J. Cory, Thomas LaDuke, Danial S. Amick, Thomas J. Loebel, Marvin Kay, Brooke M. Morgan, Matthew G. Hill, John M. Lambert, Steven L. Boles, Joseph A.M. Gingerich ...
    Series series Peopling of the Americas Publications
    Based on decades of research centered on the earliest known fluted-point producing groups in the North American midcontinent, Early Paleoindians in the Upper Midcontinent of North America: Lithic Procurement, Settlement Mobility, and Social Interaction brings together a broad array of case studies from the United States and Canada that offers fresh perspectives on how early populations utilized ... Leer más

    $71.99 USD

  • Chemical Linkers in Antibody–Drug Conjugates (ADCs)

    Edición de Floris van Delft, John M Lambert ...
    Series Libro 81 - Drug Discovery Series
    The covalent conjugation of potent cytotoxic agents to monoclonal antibodies, known as antibody-drug conjugates (ADCs) is a powerful approach in the field of targeted treatment of cancer. Clearly, both monoclonal antibody and cytotoxic payload are crucial elements in determining the clinical value of an ADC and have receive ample attention. However, the structural element connecting the two –the ... Leer más

    $224.99 USD

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  • Handbook of Cell Signaling

    Edición de Ralph A. Bradshaw, Edward A. Dennis ...
    Series series Cell Biology
    Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular ... Leer más

    $481.99 USD

  • RNA Interference (RNAi)

    de Wiley ...
    Series series Life Science Research Fundamentals
    The 2006 Nobel Prize in Physiology or Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit) or up- or down-regulate gene expression, typically by causing the destruction of specific messenger RNA (mRNA) molecules. This collection of articles begins with an introduction to ... Leer más

    $27.99 USD

  • Handbook of Cell Signaling, Three-Volume Set

    Edición de Ralph A. Bradshaw, Edward A. Dennis ...
    Series series Cell Biology
    The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The subject matter has been divided into five main parts (each of which is headed by a recognized expert in the field):* Initiation: ... Leer más

    $544.99 USD

  • Therapeutic Monoclonal Antibodies

    From Bench to Clinic

    Edición de Zhiqiang An ...
    70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies.First book to address the discovery and development of antibody therapeutics in their entirety.Most chapters contain experimental data to illustrate the principles described in them.Authors provide ... Leer más

    $198.00 USD

  • Polypharmacology in Drug Discovery

    Edición de Jens-Uwe Peters ...
    An essential outline of the main facets of polypharmacology in drug discovery researchExtending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of ... Leer más

    $127.00 USD

  • Antibody-Drug Conjugates

    The 21st Century Magic Bullets for Cancer

    Edición de Jeffrey Wang, Wei-Chiang Shen, Jennica L. Zaro ...
    Series series Biomedical and Life Sciences (R0)
    This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a ... Leer más

    $98.09 USD

  • GPCR Molecular Pharmacology and Drug Targeting

    Shifting Paradigms and New Directions

    Edición de Annette Gilchrist ...
    G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors takes a look at the way GPCRs are examined today, how they react, how their mutations lead to disease, and the ... Leer más

    $168.00 USD

  • Innovations for Next-Generation Antibody-Drug Conjugates

    Edición de Marc Damelin ...
    Series series Medicine (R0)
    Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history ... Leer más

    $143.09 USD

  • Biased Signaling in Physiology, Pharmacology and Therapeutics

    Edición de Brian J Arey ...
    Biased Signaling in Physiology, Pharmacology and Therapeutics is a unique and essential reference for the scientific community concerning how conformational-dependent activation is a common phenomenon across many classes of receptors or signaling molecules. It discusses the role of conformational dynamics in leading to signaling bias across different classes of receptors and signaling molecules. ... Leer más

    $134.99 USD

  • Peptide-based Drug Discovery

    Challenges and New Therapeutics

    Edición de Ved Srivastava ...
    Series Libro 59 - Drug Discovery Series
    With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What ... Leer más

    $225.99 USD