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Biotechnology Intelligence Unit Série de Livres électroniques

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  • 5-HT4 Receptors in the Brain and Periphery

    Modifié par Richard M. Eglen ...
    Collections series Biotechnology Intelligence Unit
    This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel ... En savoir plus

    $179.99 CAD

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  • Folding for the Synapse

    Modifié par Vincent O'Connor, Andreas Wyttenbach ...
    Collections series Biomedical and Life Sciences (R0)
    Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an ... En savoir plus

    $256.19 CAD

  • Oxidative Stress and Free Radical Damage in Neurology

    Modifié par Natan Gadoth, Hans Hilmar Göbel ...
    Collections series Biomedical and Life Sciences (R0)
    The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with ... En savoir plus

    $256.99 CAD

  • The Cannabinoid Receptors

    Modifié par Patricia H. Reggio ...
    Collections series Biomedical and Life Sciences (R0)
    As research has progressed, the cannabinoid CB 1 and CB 2 receptors have expanded significantly in importance within the neuroscience mainstream. In The Cannabinoid Receptors, leading experts introduce newcomers to the cannabinoid field with chapters covering cannabinoid ligand synthesis and structure activity relationships, the molecular pharmacology of the cannabinoid receptors and the ... En savoir plus

    $179.99 CAD

  • Blue Biotechnology

    From Gene to Bioactive Product

    Modifié par Werner E. G. Müller, Xiaohong Wang, Heinz C. Schröder ...
    Collections series Biomedical and Life Sciences (R0)
    This book describes the discovery of molecules from unexploited extreme marine environments, and presents new approaches in marine genomics. It combines the current state of knowledge in marine genomics and advanced natural products’ chemistry to pursue the sustainable production of novel secondary metabolites (lead compounds), as well as pharmacologically active peptides/proteins, with ... En savoir plus

    $204.99 CAD

  • Semaphorins

    A Diversity of Emerging Physiological and Pathological Activities

    Modifié par Atsushi Kumanogoh ...
    Collections series Biomedical and Life Sciences (R0)
    This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and ... En savoir plus

    $115.29 CAD

  • Trinucleotide Diseases and Instability

    Modifié par Ben A. Oostra ...
    Collections series Biomedical and Life Sciences (R0)
    Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 ... En savoir plus

    $64.99 CAD

  • New Strategies in Stroke Intervention

    Ionic Transporters, Pumps, and New Channels

    Modifié par Lucio Annunziato ...
    Collections series Biomedical and Life Sciences (R0)
    Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for ... En savoir plus

    $128.99 CAD

  • Astrocytes in (Patho)Physiology of the Nervous System

    Modifié par Vladimir Parpura, Philip G. Haydon ...
    Collections series Biomedical and Life Sciences (R0)
    Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately ... En savoir plus

    $256.19 CAD

  • Molecular and Functional Models in Neuropsychiatry

    Modifié par Jim J. Hagan ...
    Collections series Biomedical and Life Sciences (R0)
    The development of more effective treatments for neuropsychiatric disorders requires scientific progress on a broad front. Animal models have a vital role to play in advancing the field. When deployed in conjunction with detailed study of these diseases in man they bring the power to make controlled experimental interventions which allow the functional consequences of genetic variations and ... En savoir plus

    $256.99 CAD

  • Angiogenesis Modulations in Health and Disease

    Practical Applications of Pro- and Anti-angiogenesis Targets

    Modifié par Paul J. Davis, Shaker A. Mousa ...
    Collections series Biomedical and Life Sciences (R0)
    This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in ... En savoir plus

    $179.39 CAD

  • Müller Cells in the Healthy and Diseased Retina

    par Andreas Reichenbach, Andreas Bringmann ...
    Collections series Biomedical and Life Sciences (R0)
    Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient ... En savoir plus

    $306.99 CAD